What is XEMBIFY?
XEMBIFY is a 20% subcutaneous immune globulin (SCIG) replacement therapy used to treat PI (primary humoral immunodeficiency disease) in patients 2 years of age and older.
What's the difference between subcutaneous IG therapy and intravenous IG therapy?
Subcutaneous immune globulin (SCIG) is administered under the skin while intravenous immune globulin (IVIG) therapy is administered through a vein. Different IG products have different concentrations. This means they may require more or less volume to be infused. XEMBIFY is a 20% subcutaneous immune globulin (SCIG) replacement therapy used to treat PI in patients 2 years of age and older.
Can XEMBIFY only be used subcutaneously?
XEMBIFY is a subcutaneous immune globulin (SCIG) replacement therapy used to treat PI in patients 2 years of age and older. XEMBIFY can only be administered by subcutaneous infusion. Some patients infuse XEMBIFY as often as every day, while other patients infuse once per week. Talk to your doctor about your infusion schedule.
How is XEMBIFY made?
XEMBIFY is medicine made from healthy proteins taken from human plasma and contains purified antibodies. It is formulated with no sugar and very low amounts of sodium, which may make it suitable for people with diabetes and heart disease. Learn more about XEMBIFY.
Are there any additives or preservatives included in XEMBIFY?
XEMBIFY contains no preservatives and the vial is not made with natural rubber latex.
How well does XEMBIFY work?
In a clinical study, people taking XEMBIFY saw improvement in their symptoms of PI and the impact PI had on their lives. Within a year, people taking XEMBIFY experienced:
- 0 serious bacterial infections1*
- Less than 3 days of missed work/school1
- 0 hospitalizations due to infections1†
How well is XEMBIFY tolerated?
The most common side effects in a clinical study with PI patients who received XEMBIFY were1:
- Infusion-site reactions such as redness, pain, puffiness, swelling, bruising, nodule or scab formation, itching, and firmness
- Cough and diarrhea
Tell your healthcare provider if you have or ever had:
- A serious reaction to other medicines that contain immune globulin
- An immunoglobulin A (IgA) deficiency
- A history of heart or blood vessel disease
- A risk factor for blood clots
- Inability to move over the course of a few hours
Can XEMBIFY be used during pregnancy?
It is not known whether XEMBIFY can cause fetal harm when administered to a pregnant woman or if it can affect reproduction. Talk to your doctor if you are pregnant or may become pregnant.